China's Breakthrough in Scientific Problems to Cultivate "Boanna Miniature Pigs"

The problem that the international scientific community had not overcome in the past half a century—the inbred strains of large mammal experimental animals, was successfully cracked by Chinese scientists. Authoritative experts believe that the Yunnan Bunao University's successful cultivation of the Banna miniature pig inbred is a major scientific and technological achievement of China's original innovation and is of great significance to biomedical research. Since 1980, the research group headed by Professor Zeng Yangzhi of Yunnan Agricultural University has started the research on breeding of the first inbred strain in China. They targeted Yunnan's fine local breeds, the Jinnaxiaoying pigs. From the first generation, they adopted two generations of inbreds: parent-child marriage (father or daughter) or full-sib mating (brothers and sisters or siblings) for 20 consecutive generations. Successfully established inbred lines of large mammals. The majority of hereditary diseases in pigs are very similar to those in humans. More than 20 hereditary diseases that occurred during the breeding of Banna miniature pig inbreds were found in human newborn infants and adults. By studying the hereditary diseases of Banna miniature pigs, we can solve a variety of genetic diseases in humans. At the same time, some tissue structures of pigskin are similar to those of human skin. Therefore, if pigskins of hairless Banna miniature pigs are combined with human skin after burns, both the pain and infection after burns can be reduced without repulsion. Phenomenon, blood vessels healing is also very good, burn patients will benefit a lot. Experts pointed out that the completion of the Banna miniature pig inbred line for 20 generations will provide large mammals with highly homozygous genes, clear genetic background, and genetic diversity for biomedical research, xenotransplantation, and transgenic animal research. It is expected that it will gradually develop and form a unique biotechnology industry.

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