AvantGen and Tanabe expand cooperation in the field of antibody therapeutic drug discovery

AvantGen will develop more antibody-based anticancer drugs for Tanabe Research Laboratories USA using its proprietary human antibody yeast display platform.

AvantGen, Inc. is a biotechnology company with an antibody discovery and optimization platform in San Diego, USA. The company today announced the successful completion of Tanabe Research Laboratories USA, Inc. (TRL)'s first antibody-based anticancer drug discovery program and has launched TRL's second project. Under the terms of the partnership, AvantGen is responsible for the development of novel antibodies targeting specific cancer targets using its proprietary human antibody yeast display technology platform. TRL owns the global development and commercialization rights of antibodies discovered by AvantGen. AvantGen will receive upfront payments, milestone payments and royalties related to the development and sale of any derivative products generated by the partnership.

Dr. Fan Xiaomin, founder and president of AvantGen, said: “Using numerous NIH SBIR I and II funding projects, AvantGen's antibody discovery and optimization platform has been widely validated in more than 100 targets. The second project with TRL is The 15th new antibody discovery project launched by our corporate partners since the company recently launched a new top-of-the-line human antibody discovery and optimization platform. The platform utilizes a powerful yeast display system, a large database of human natural antibodies, and whole body antibodies. Advanced technologies such as libraries to develop antibodies to meet challenging design goals in therapeutic, diagnostic and research fields."

Dr. Roland Newman, Chief Scientific Officer of TRL, said: “AvantGen has been highly collaborative in developing antibody therapy drug discovery projects, completed ahead of schedule, and antibodies can achieve TRL design goals without further optimization. We look forward to the second project and Collaboration in other projects in the future."


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