Model NO.: 220127-57-1
Quality Standard: Bp, USP, Ep, Cp
Usage: Treating Cancer
Appearence: White to Beige
Payment Method: T/T, Western Union, Money Gram, Paypal
Delivery Time: Shipped in 3 Days After Payment
Mf: C30h35n7o4s
Shipping Method: EMS, DHL, FedEx, etc(Door-to-Door)
Trademark: Shinrezing
Transport Package: Foil Bag, Drum or Carton (Discreet Package)
Origin: Hubei
Model NO.: 220127-57-1
Quality Standard: Bp, USP, Ep, Cp
Usage: Treating Cancer
Appearence: White to Beige
Payment Method: T/T, Western Union, Money Gram, Paypal
Delivery Time: Shipped in 3 Days After Payment
Mf: C30h35n7o4s
Shipping Method: EMS, DHL, FedEx, etc(Door-to-Door)
Trademark: Shinrezing
Transport Package: Foil Bag, Drum or Carton (Discreet Package)
Origin: Hubei
Product Description
Imatinib Introduction
Imatinib, sold under the brand names Gleevec and Glivec, used in the treatment of multiple cancers, most notably Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML).  Due in large part to the development of Gleevec and related drugs having a similar mechanism of action, the five year survival rate for people with chronic myeloid leukemia nearly doubled from 31% in 1993 (before Gleevec's 2001 FDA approval) to 59% for those diagnosed between 2003 and 2009.  Median survival for imatinib-treated people with gastrointestinal stromal tumors (GIST) is nearly 5 years compared to 9 to 20 months in the pre-imatinib-era.
Imatinib Mesylate Basic Info.
Other Name:Glivec;gleevec;imatinib methanesulfonate;imatinib mesilate;Imatinibmesylate;4-[(4-methylpiperazin-1-yl)methyl]-n-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide methanesulfonate;4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide monomethanesulfonate
CAS:220127-57-1
MF:C30H35N7O4S
MW:589.71
Assay:99%min
Appearence:White powder
Drug category:Anti tumor drug
Purpose:A tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL).
Imatinib Mesylate Application:
Compared to older drugs imatinib has a relatively benign side effect profile, allowing many patients to live a normal lifestyle.  Imatinib is a tyrosine-kinase inhibitor. It kills cancer cells by blocking the action of tyrosine kinases. In order to survive, cells need signaling through proteins (signal cascade) to keep them alive. Some of the proteins in this cascade use a phosphate group as an "on" switch. This phosphate group is added by a tyrosine kinase enzyme. In healthy cells, these tyrosine kinase enzymes are turned on and off as needed. In Ph-positive CML cells, one tyrosine kinase enzyme, BCR-Abl, is stuck on the "on" position, and keeps adding phosphate groups. Imatinib blocks this BCR-Abl enzyme, and stops it from adding phosphate groups. As a result, these cells stop growing, and even die by a process of cell death (apoptosis).  Because the BCR-Abl tyrosine kinase enzyme exists only in cancer cells and not in healthy cells, imatinib works as a form of targeted therapy-only cancer cells are killed through the drug's action.[6] In this regard, imatinib was one of the first cancer therapies to show the potential for such targeted action, and is often cited as a paradigm for research in cancer therapeutics.
Compared to older drugs imatinib has a relatively benign side effect profile, allowing many patients to live a normal lifestyle.  Imatinib is a tyrosine-kinase inhibitor. It kills cancer cells by blocking the action of tyrosine kinases. In order to survive, cells need signaling through proteins (signal cascade) to keep them alive. Some of the proteins in this cascade use a phosphate group as an "on" switch. This phosphate group is added by a tyrosine kinase enzyme. In healthy cells, these tyrosine kinase enzymes are turned on and off as needed. In Ph-positive CML cells, one tyrosine kinase enzyme, BCR-Abl, is stuck on the "on" position, and keeps adding phosphate groups. Imatinib blocks this BCR-Abl enzyme, and stops it from adding phosphate groups. As a result, these cells stop growing, and even die by a process of cell death (apoptosis).  Because the BCR-Abl tyrosine kinase enzyme exists only in cancer cells and not in healthy cells, imatinib works as a form of targeted therapy-only cancer cells are killed through the drug's action.[6] In this regard, imatinib was one of the first cancer therapies to show the potential for such targeted action, and is often cited as a paradigm for research in cancer therapeutics.
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|
Peptide List  | |
| Product Name | Specification |
| ACE 031 | 1 mg/vial, 10 vials/kit |
| Follistatin 315 | 1 mg/vial, 10 vials/kit |
| Follistatin 344 | 1 mg/vial, 10 vials/kit |
| ***************************** | ***************************** |
| MGF | 2 mg/vial, 10 vials/kit |
| PEG -Â MGF | 2 mg/vial, 10 vials/kit |
| DSIP | 2 mg/vial, 10 vials/kit |
| TB500 | 2 mg/vial, 10 vials/kit |
| Oxytocin | 2 mg/vial, 10 vials/kit |
| Hexarelin | 2 mg/vial, 10 vials/kit |
| Triptorelin | 2 mg/vial, 10 vials/kit |
| Ipamorelin | 2 mg/vial, 10 vials/kit |
| Sermorelin | 2 mg/vial, 10 vials/kit |
| Gonadorelin | 2 mg/vial, 10 vials/kit |
| Tesamorelin | 2 mg/vial, 10 vials/kit |
| BPC 157 | 2 mg/vial, 10 vials/kit |
| AOD-9604 | 2 mg/vial, 10 vials/kit |
| H 176-191 | 2 mg/vial, 10 vials/kit |
| CJC-1295 | 2 mg/vial, 10 vials/kit |
| CJC-1295 DAC | 2 mg/vial, 10 vials/kit |
| ***************************** | ***************************** |
| GHRP-2 | 5 mg/vial, 10 vials/kit |
| GHRP-6 | 5 mg/vial, 10 vials/kit |
| Selank | 5 mg/vial, 10 vials/kit |
| ***************************** | ***************************** |
| GHRP-2 | 10 mg/vial, 10 vials/kit |
| GHRP-6 | 10 mg/vial, 10 vials/kit |
| Epitalon | 10 mg/vial, 10 vials/kit |
| PT-141 | 10 mg/vial, 10 vials/kit |
| Gonadorelin | 10 mg/vial, 10 vials/kit |
| Melanotan II | 10 mg/vial, 10 vials/kit |
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Packaging
Shipping Method
Company Information
Hubei Shinrezing Pharmaceutical Technology Co.,Ltd.(hereafter shorted as Shinrezing) is located in Wuhan Donghu High-Tech Economic Development Zone and established in 2008 with registered capital is RMB 10 million yuan (about USD 1.5 million ). Its manufacturing base is located in Dawu Industrial Park in Dawu County, Xiaogan City, Hubei Province which is built in 2010 with 25,000 square meters covered area.
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Shinrezing is a rapid growing enterprise, which integrates the production, R&D, sales and trading of APIs, steroid raw materials, pharmaceutical intermediates, plant extracts, other kinds of organic intermediates etc. Shinrezing is not only a manufacturing company but also a trade company, it also has very good cooperation relationships with some manufacturers qualified with GMP, DMF to meet the different customers' needs from grams to tonnage quantity, which makes Shinrezing to be more flexible and easily to supply highly cost-effective products with high quality and better service to customers.
Shinrezing always stands in high starting, high stand and high quality, and masters strict management for production procedure and quality control. All the products must pass our quality test before being sending to customers. Shinrezing's products have been exported to more than 50 countries and regions all over the world, including United States, Europe, Japan, Korea, Russia, Hong kong, Taiwan and so on, and enjoy a good reputation from domestic and oversea customers
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Shinrezing's mission is: "Innovative and Pragmatic, Mutual Benefits, Serve the World". Every staff member will keep this in mind all the time, and enforce it at every detail of operation and management of the company. We are always trying our best to offer the best services and the most competitive prices with high quality goods for our customers. All honors belong to the past, Shinrezing people will do their best to develop and produce more perfect product and contribute to the chemical pharmaceutical industries worldwide.
We are confident that Shinrezing will be your best solution.
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