Pill robots may change the mode of administration of biological agents

Many biologic drugs are very "feeling", they can only be administered by injection, and if they are taken orally, the digestive system will destroy the effective structure. However, injections are a hard-to-follow thing, especially for some chronic diseases, which require long-term maintenance and treatment. For example, diabetes, which we are familiar with, requires accurate daily use of insulin to balance blood sugar levels.

The pain and psychological stress caused by long-term drug injection are hard to ignore. Is there any way to achieve the same therapeutic effect in other more friendly ways?

药丸机器人或许将变革生物制剂的给药模式

Image source: medGadget

A company called Rani Therapeutics has invented a pill-type drug delivery device that can be used for the delivery of biological agents such as insulin in the gut. The delivery of insulin has always been a very interesting research direction in the scientific community. Scientists have adopted a variety of ideas, such as inhalation, slow release, insulin pump, etc., and how does this device find another way to do this?

药丸机器人或许将变革生物制剂的给药模式

The CEO of Rani Therapeutics is Mr. Mir Imran. Image Source: medGadget

The CEO of Rani Therapeutics is Mr. Mir Imran, a well-known figure in the medical invention industry. He is a prolific inventor of medical devices, founded more than 20 life science companies, and has more than 300 issued patents, most notably his pioneering FDA-approved automatic implantable cardioverter defibrillator. The inventor has such a remarkable invention achievement, and naturally this pill-type drug delivery device is also inevitably bright.

药丸机器人或许将变革生物制剂的给药模式

Rani drug delivery device image source: medGadget

Maxillofacial Fixation

Maxillofacial fixation system -- micro-plate for cranial and maxillofacial fracture fixation, designed for the surgical treatment of maxillofacial trauma fractures, suitable for the forehead, nose, orbit, zygomatic, maxillary region, and pediatric craniofacial bones.

The system is an orthopedic surgical instrument for neurosurgical tools. The maxillofacial fixation system includes micro-plates, straight plates, L-shaped plates, T-shaped plates, Y-shaped plates, double Y-shaped plates, H-shaped plates for cranial and maxillofacial fractures. The product range is complete, covering three-dimensional titanium mesh, self-drilling rotary bone screws, anatomical orbital floor plates, orthodontic nails, etc. However, the facial anatomical structure is special, and the screw plate needs to be placed away from the fracture line and avoid important anatomical structures such as nerves and teeth roots. Therefore, the specifications of the screw plate system are required to be as diverse as possible in order to be used in different bone structures, such as different radian, length, and number of screw holes. The bone plates forcranial and maxillofacial fractures are mainly divided into 1.5mm, 2.0mm and 2.4mm systems.

Titanium (including pure titanium and titanium alloy) is the most common material for hard tissue implants. Its elastic modulus and tensile strength are higher than those of human bone, and it is better than other metal materials such as nickel-titanium alloy and cobalt-chromium alloy in terms of biocompatibility and corrosion resistance. Our maxillofacial plate is made of titanium, and the self-tapping screws are mainly made of titanium alloy.

Jaw fractures include maxillary fractures and mandibular fractures. According to whether the fracture trauma is exposed, it can be divided into open fracture and closed fracture. Trauma is the most common cause of jaw fracture, which usually includes hit, traffic injury, fall injury, firearm injury, and a few iatrogenic injuries. All are caused by external forces acting directly or indirectly on the maxillofacial region. With the popularization of motor vehicles, the proportion of jaw fractures caused by traffic accidents has increased year by year, which has become the main cause of jaw fractures. In addition, neoplastic lesions in the maxillofacial region often lead to pathological jaw fractures.

In summary, maxillofacial fixation system has been widely used in clinical maxillofacial surgery, plastic surgery and ENT, and has a relatively mature market.

Titanium Plate,Rectangular Plate,orthognathic surgery,oral and maxillofacial

Jiangsu Aomed Ortho Medical Technology Co.,Ltd , https://www.aomedortho.com